Name :
HAP1 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
HAP1 Rabbit Polyclonal antibody. Positive WB detected in fetal human brain tissue. Positive IF detected in SH-SY5Y cells. Positive IHC detected in mouse brain tissue. Observed molecular weight by Western-blot: 75-80 kDa
Tested applications :
ELISA, WB, IHC, IF
Species reactivity :
Human, Mouse; other species not tested.
Alternative names :
HAP 1 antibody; HAP1 antibody; HAP2 antibody; hHLP1 antibody; HIP5 antibody; HLP antibody; HLP1 antibody; Neuroan 1 antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of HAP1 recombinant protein (Accession Number: NM_003949). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:200-1:2000IHC: 1:20-1:200IF: 1:20-1:200
Background :
HAP1 (Huntingtin-associated protein 1) was originally identified as neuronal protein that specifically associates with HTT/huntingtin and the binding is enhanced by an expanded polyglutamine repeat within HTT. HTT is expressed ubiquitously, while HAP1 is expressed predominantly in the central nervous system (CNS). Both HTT and HAP1 participate in intracellular trafficking. HAP1 is involved in the vesicular transport, gene transcription regulation, membrane receptor trafficking and other functions such as calcium release and protein aggregation (PMID: 19262167).
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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