Name :
KDM4B Polyclonal Antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
Polyclonal antibody to KDM4B
Tested applications :
WB, IHC, IF
Species reactivity :
Human, Mouse, Rat
Alternative names :
KDM4B antibody; JMJD2B antibody; TDRD14B antibody; lysine demethylase 4B antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human KDM4B (NP_055830.1).
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage instructions :
Store at -20℃. Avoid freeze / thaw cycles.
Applications :
WB 1:500 – 1:2000IHC 1:50 – 1:200IF 1:50 – 1:200
Background :
Histone demethylase that specifically demethylates ‘Lys-9’ of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 ‘Lys-4’, H3 ‘Lys-27’, H3 ‘Lys-36’ nor H4 ‘Lys-20’. Only able to demethylate trimethylated H3 ‘Lys-9’, with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate.
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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