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Name :
MARK1 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
MARK1 Rabbit Polyclonal antibody. Positive IP detected in mouse brain tissue. Positive WB detected in mouse brain tissue, HeLa cells, mouse heart tissue, mouse kidney tissue, SH-SY5Y cells. Observed molecular weight by Western-blot: 85 kDa,89 kDa,72 kDa

Tested applications :
ELISA, WB, IP

Species reactivity :
Human,Mouse,Rat; other species not tested.

Alternative names :
KIAA1477 antibody; MARK antibody; MARK1 antibody

Immunogen :
Human MARK1 Recombinant protein (GST tag)

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of MARK1 recombinant protein (Accession Number: NM_018650). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:1000-1:10000IP: 1:500-1:5000

Background :
MARK1 represents MAP/microtubule affinity-regulating kinase 1

References :
Goodwin JM, Svensson RU, Lou HJ, Winslow MM, Turk BE, Shaw RJ. An AMPK-independent signaling pathway downstream of the LKB1 tumor suppressor controls Snail1 and metastatic potential. Molecular cell. 55(3):436-50. 2014. Bernard LP, Zhang H. MARK/Par1 Kinase Is Activated Downstream of NMDA Receptors through a PKA-Dependent Mechanism. PloS one. 10(5):e0124816. 2015.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel