Name :
MED19 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
MED19 Rabbit Polyclonal antibody. Positive IHC detected in human testis tissue. Positive WB detected in human testis tissue. Observed molecular weight by Western-blot: 31 kDa
Tested applications :
ELISA, WB, IHC
Species reactivity :
Human,Mouse,Rat; other species not tested.
Alternative names :
DT2P1G7 antibody; LCMR1 antibody; MED19 antibody; mediator complex subunit 19 antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of MED19 recombinant protein (Accession Number: NM_153450). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:200-1:1000IHC: 1:20-1:200
Background :
Mediator of RNA polymerase II transcription subunit 19 (MED19) is a component of the Mediator complex, which is a coactivator for DNA-binding factors that activate transcription via RNA polymerase II (PMID: 12584197). Mediator complex is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors (PMID: 15175163). MED19 may be a novel proliferation regulator that promotes lung cancer and gastric cancer progression and cellular growth (PMID: 21519921)(PMID: 22565189).
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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