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Name :
MIXL1 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
MIXL1 Rabbit Polyclonal antibody. Positive WB detected in HEK-293 cells, H7ES cells, rat pancreas tissue. Observed molecular weight by Western-blot: 20 kDa

Tested applications :
ELISA, WB

Species reactivity :
Human, Rat; other species not tested.

Alternative names :
hMix antibody; Homeobox protein MIXL1 antibody; Homeodomain protein MIX antibody; MILD1 antibody; MIX antibody; Mix.1 homeobox like protein antibody; MIX1 homeobox like protein 1 antibody; MIXL antibody; MIXL1 antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of MIXL1 recombinant protein (Accession Number: NM_031944). Purification method: Antigen Affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:500-1:5000

Background :
Mix1 homeobox-like 1 (MIXL1) Transcription factor that play a central role in proper axial mesendoderm morphogenesis and endoderm formation. Required for efficient differentiation of cells from the primitive streak stage to blood, by acting early in the recruitment and/or expansion of mesodermal progenitors to the hemangioblastic and hematopoietic lineages. Also involved in the morphogenesis of the heart and the gut during embryogenesis. Acts as a negative regulator of brachyury expression. This antibody is specific to MIXL1.

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel