Name :
HTR3A antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
HTR3A Rabbit Polyclonal antibody. Positive WB detected in mouse lung tissue, human brain tissue. Positive IHC detected in human small intestine tissue, human prostate cancer tissue. Observed molecular weight by Western-blot: 55 kDa
Tested applications :
ELISA, IHC, WB
Species reactivity :
Human,Mouse,Rat; other species not tested.
Alternative names :
5 HT 3 antibody; 5 HT3 A antibody; 5 HT3A antibody; 5 HT3R antibody; 5 hydroxytryptamine receptor 3 antibody; 5HT3R antibody; HTR3 antibody; HTR3A antibody; Serotonin receptor 3A antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of HTR3A recombinant protein (Accession Number: NM_000869). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:200-1:2000IHC: 1:20-1:200
Background :
HTR3A (5-hydroxytryptamine receptor 3A, 5-HT3A) belongs to the ligand-gated ion channel receptor superfamily. It is the subunit A of the type 3 receptor for 5-hydroxytryptamine (5-HT, serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. So far, five distinct 5-HT3 receptor subunits (A-E) have been identified. HTR3A can form functional homomers or heteromers with HTR3B or HTR3C or HTR3D or HTR3E. 5-HT3 receptors are capable of mediating fast excitatory neurotransmission in the CNS and peripheral nervous system (PNS). (PMID: 23038271; 17073663)
References :
Loyd DR, Sun XX, Locke EE, Salas MM, Hargreaves KM. Sex differences in serotonin enhancement of capsaicin-evoked calcitonin gene-related peptide release from human dental pulp. Pain. 153(10):2061-7. 2012.
Related websites: https://www.medchemexpress.com/antibodies.html
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