Name :
IDH1 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
IDH1 Mouse Monoclonal antibody. Positive WB detected in MCF-7 cells, HepG2 cells. Positive IF detected in HepG2 cells. Positive IHC detected in human pancreas tissue, human gliomas tissue. Observed molecular weight by Western-blot: 46 kDa
Tested applications :
ELISA, WB, IHC, IF
Species reactivity :
Human; other species not tested.
Alternative names :
IDCD antibody; IDH antibody; IDH1 antibody; IDP antibody; IDPC antibody; NADP(+) specific ICDH antibody; Oxalosuccinate decarboxylase antibody; PICD antibody
Immunogen :
Isotype :
Mouse IgG1
Preparation :
This antibody was obtained by immunization of IDH1 recombinant protein (Accession Number: NM_005896). Purification method: Protein G purified.
Clonality :
Monoclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:500-1:5000IHC: 1:20-1:200IF: 1:50-1:500
Background :
IDH1, also named as PICD and IDP, belongs to the isocitrate and isopropylmalate dehydrogenases family. It is a common feature of a major subset of primary human brain cancers. It can form a homodimer(PMID:15173171).IDH1 mutation is always heterozygotic and IDH1 functions as a dimer, theoretically there will be 25% each wild type and mutant homo-dimers and 50% hetero-dimers present in the tumor cells(PMID:21079649 ).
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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