Name :
14-3-3 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
14-3-3 Mouse Monoclonal antibody. Positive FC detected in HeLa cells. Positive IF detected in HepG2 cells. Positive IHC detected in rat brain tissue. Positive WB detected in human brain tissue, HeLa cells, HepG2 cells. Observed molecular weight by Western-blot: 31 kDa,28 kDa
Tested applications :
ELISA, WB, IHC, IF, FC
Species reactivity :
Human, Rat; other species not tested.
Alternative names :
14 3 3 antibody; 14 3 3 protein T cell antibody; 14 3 3 protein tau antibody; 14 3 3 protein theta antibody; 14-3-3 tau antibody; HS1 antibody; Protein HS1 antibody; YWHAQ antibody
Immunogen :
Human 14-3-3 Recombinant protein (His tag)
Isotype :
Mouse IgG1
Preparation :
This antibody was obtained by immunization of 14-3-3 recombinant protein (Accession Number: NM_006826). Purification method: Protein G purified.
Clonality :
Monoclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:500-1:5000IHC: 1:20-1:200IF: 1:20-1:200
Background :
14-3-3 proteins interact with a wide spectrum of proteins and possess diverse functions. Mammals express seven distinct 14-3-3 isoforms (gamma, epsilon, beta, zeta, sigma, theta, tau) that form multiple homo- and hetero- dimmers. 14-3-3 proteins display the highest expression levels in the brain, and have been implicated in several neurodegenerative diseases, including Alzheimer’s disease and amyotrophic lateral sclerosis. 66061-1-Ig recognizes 14-3-3 tau (YWHAQ), eta (YWHAH), and zeta (YWHAZ), but not epsilon (YWHAE).
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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