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Name :
GNAI2 Polyclonal Antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
Polyclonal antibody to GNAI2

Tested applications :
WB, IHC

Species reactivity :
Human, Mouse, Rat

Alternative names :
GNAI2 antibody; GIP antibody; GNAI2B antibody; H_LUCA15.1 antibody; H_LUCA16.1 antibody; G protein subunit alpha i2 antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-355 of human GNAI2 (NP_002061.1).

Clonality :
Polyclonal

Formulation :
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage instructions :
Store at -20℃. Avoid freeze / thaw cycles.

Applications :
WB 1:500 – 1:2000IHC 1:50 – 1:200

Background :
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. May play a role in cell division.; Isoform sGi2: Regulates the cell surface density of dopamine receptors DRD2 by sequestrating them as an intracellular pool.

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel