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Name :
GNAO1 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
GNAO1 Rabbit Polyclonal antibody. Positive IP detected in mouse brain tissue. Positive WB detected in rat brain tissue, human brain tissue, human liver tissue, mouse testis tissue, Y79 cells. Positive IHC detected in human gliomas tissue. Observed molecular weight by Western-blot: 40 kDa

Tested applications :
ELISA, IHC, WB, IP

Species reactivity :
Human,Mouse,Rat; other species not tested.

Alternative names :
DKFZp686O0962 antibody; G ALPHA o antibody; GNAO antibody; GNAO1 antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of GNAO1 recombinant protein (Accession Number: BC030027). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:200-1:2000IP: 1:200-1:2000IHC: 1:20-1:200

Background :
GNAO1 represents guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O

References :
Pei X, Zhang J, Wu L. The down-regulation of GNAO1 and its promoting role in hepatocellular carcinoma. Bioscience reports. 33(5):. 2013. Liu Z, Zhang J, Wu L, Liu J, Zhang M. Overexpression of GNAO1 correlates with poor prognosis in patients with gastric cancer and plays a role in gastric cancer cell proliferation and apoptosis. International journal of molecular medicine. 33(3):589-96. 2014.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel