Share this post on:

Name :
GNAS antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
GNAS Rabbit Polyclonal antibody. Positive IP detected in mouse liver tissue. Positive WB detected in mouse liver tissue. Positive IHC detected in human pancreas tissue. Observed molecular weight by Western-blot: 46 kDa

Tested applications :

Species reactivity :
Human,Mouse,Rat; other species not tested.

Alternative names :
AHO antibody; C20orf45 antibody; dJ309F20.1.1 antibody; dJ806M20.3.3 antibody; GNAS antibody; GNAS complex lOCus antibody; GNAS1 antibody; GPSA antibody; GSA antibody; GSP antibody; NESP antibody; PHP1A antibody; PHP1B antibody; POH antibody

Immunogen :
Human NESP55,GNAS Recombinant protein (GST tag)

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of GNAS recombinant protein (Accession Number: NM_000516). Purification method: Antigen affinity purified.

Clonality :

Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:500-1:5000IP: 1:200-1:1000IHC: 1:20-1:200

Background :
Guanine nucleotide binding protein (G protein), alpha stimulating activity polypeptide 1 (GNAS1) is the ubiquitously expressed heterotrimeric G protein that couples receptors to the effector enzyme adenylyl cyclase and is required for receptor-stimulated intracellular cAMP generation. Mutations of Gs(alpha) residues involved in the GTPase reaction that lead to constitutive activation are present in endocrine tumors, fibrous dysplasia of bone, and McCune-Albright syndrome. The molecular weight of Gs(alpha) protein is about 46 kDa.

References :
Gemoll T, Roblick UJ, Szymczak S. HDAC2 and TXNL1 distinguish aneuploid from diploid colorectal cancers. Cellular and molecular life sciences : CMLS. 68(19):3261-74. 2011.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites:
Popular product recommendations:
Acetyl CoA synthetaseAntibody
Glutathione Synthetase Antibody

Share this post on:

Author: Gardos- Channel