Name :
GNAS antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
GNAS Rabbit Polyclonal antibody. Positive IP detected in mouse liver tissue. Positive WB detected in mouse liver tissue. Positive IHC detected in human pancreas tissue. Observed molecular weight by Western-blot: 46 kDa
Tested applications :
ELISA, IP, IHC, WB
Species reactivity :
Human,Mouse,Rat; other species not tested.
Alternative names :
AHO antibody; C20orf45 antibody; dJ309F20.1.1 antibody; dJ806M20.3.3 antibody; GNAS antibody; GNAS complex lOCus antibody; GNAS1 antibody; GPSA antibody; GSA antibody; GSP antibody; NESP antibody; PHP1A antibody; PHP1B antibody; POH antibody
Immunogen :
Human NESP55,GNAS Recombinant protein (GST tag)
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of GNAS recombinant protein (Accession Number: NM_000516). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:500-1:5000IP: 1:200-1:1000IHC: 1:20-1:200
Background :
Guanine nucleotide binding protein (G protein), alpha stimulating activity polypeptide 1 (GNAS1) is the ubiquitously expressed heterotrimeric G protein that couples receptors to the effector enzyme adenylyl cyclase and is required for receptor-stimulated intracellular cAMP generation. Mutations of Gs(alpha) residues involved in the GTPase reaction that lead to constitutive activation are present in endocrine tumors, fibrous dysplasia of bone, and McCune-Albright syndrome. The molecular weight of Gs(alpha) protein is about 46 kDa.
References :
Gemoll T, Roblick UJ, Szymczak S. HDAC2 and TXNL1 distinguish aneuploid from diploid colorectal cancers. Cellular and molecular life sciences : CMLS. 68(19):3261-74. 2011.
Related websites: https://www.medchemexpress.com/antibodies.html
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