Anti-Bad Rabbit antibody | Gardos-Channel-gardos-channel.com

Name :
Anti-Bad Rabbit antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
Bad Rabbit polyclonal antibody

Tested applications :
WB, IHC-P, ICC/IF, FC, IP

Species reactivity :
Human, Mouse, Rat

Alternative names :
BBC2; BCL2L8 antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
Antigen: A synthetic peptide of human Bad

Clonality :
Polyclonal

Formulation :
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.

Storage instructions :
Store at -20°C. Stable for 12 months from date of receipt.

Applications :
WB: 1/1000IHC: 1/50ICC/IF: 1/50FC: 1/20IP: 1/20

Background :
Swiss-Prot Acc.Q92934.Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2 . Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel

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