Share this post on:

Name :
GPM6A antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
GPM6A Rabbit Polyclonal antibody. Positive IP detected in mouse brain tissue. Positive WB detected in mouse retina tissue, rat brain tissue. Positive IHC detected in human brain tissue. Observed molecular weight by Western-blot: 31 kDa

Tested applications :

Species reactivity :
Human, Mouse, Rat; other species not tested.

Alternative names :
glycoprotein M6A antibody; GPM6 antibody; GPM6A antibody; M6A antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of GPM6A recombinant protein (Accession Number: NM_201591). Purification method: Antigen affinity purified.

Clonality :

Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:200-1:2000IP: 1:200-1:2000IHC: 1:20-1:200

Background :
Glycoprotein M6A (GPM6A, or M6A) is known as a multi-pass transmembrane protein and an abundant cell surface protein on neurons in the central nervous system (CNS). M6A belongs to the myelin proteolipid protein family and is involved in neuronal differentiation, including differentiation and migration of neuronal stem cell. M6A is identified as a retinal membrane protein that is strongly expressed at embryonic stages. In mouse adult retina, M6A plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation via regulation of MAPK and Src signaling pathways.

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites:
Popular product recommendations:
HMGB1 Antibody
AMPK alpha 2 Antibody (YA623)

Share this post on:

Author: Gardos- Channel