Name :
GPM6A antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
GPM6A Rabbit Polyclonal antibody. Positive IP detected in mouse brain tissue. Positive WB detected in mouse retina tissue, rat brain tissue. Positive IHC detected in human brain tissue. Observed molecular weight by Western-blot: 31 kDa
Tested applications :
ELISA, WB, IP, IHC
Species reactivity :
Human, Mouse, Rat; other species not tested.
Alternative names :
glycoprotein M6A antibody; GPM6 antibody; GPM6A antibody; M6A antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of GPM6A recombinant protein (Accession Number: NM_201591). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:200-1:2000IP: 1:200-1:2000IHC: 1:20-1:200
Background :
Glycoprotein M6A (GPM6A, or M6A) is known as a multi-pass transmembrane protein and an abundant cell surface protein on neurons in the central nervous system (CNS). M6A belongs to the myelin proteolipid protein family and is involved in neuronal differentiation, including differentiation and migration of neuronal stem cell. M6A is identified as a retinal membrane protein that is strongly expressed at embryonic stages. In mouse adult retina, M6A plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation via regulation of MAPK and Src signaling pathways.
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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