Anti-Bak Rabbit antibody | Gardos-Channel-gardos-channel.com

Name :
Anti-Bak Rabbit antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
Bak Rabbit polyclonal antibody

Tested applications :
WB, IHC-P, ICC/IF, FC, IP

Species reactivity :
Human

Alternative names :
BAK; CDN1; BCL2L7; BAK-LIKE antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
Antigen: A synthetic peptide of human Bak

Clonality :
Polyclonal

Formulation :
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.

Storage instructions :
Store at -20°C. Stable for 12 months from date of receipt.

Applications :
WB: 1/1000IHC: 1/20ICC/IF: 1/50FC: 1/20IP: 1/20

Background :
Swiss-Prot Acc.Q16611.Plays a role in the mitochondrial apoptosic process. Upon arrival of cell death signals, promotes mitochondrial outer membrane (MOM) permeabilization by oligomerizing to form pores within the MOM. This releases apoptogenic factors into the cytosol, including cytochrome c, promoting the activation of caspase 9 which in turn processes and activates the effector caspases.

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel

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