Name :
GPX5 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
GPX5 Rabbit Polyclonal antibody. Positive IHC detected in human testis. Positive WB detected in human testis tissue, mouse liver tissue. Observed molecular weight by Western-blot: 25kd
Tested applications :
ELISA, WB, IHC
Species reactivity :
human; other species not tested.
Alternative names :
GPX5 antibody; GSHPx 5 antibody; Glutathione peroxidase 5 antibody; GPx 5 antibody; EGLP antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of Peptide (Accession Number: NM_001509). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:200-1:2000IHC: 1:20-1:200
Background :
GPX5 belongs to the glutathione peroxidase family. GPX5 protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. Catalytic the reaction: 2 glutathione + H2O2 = glutathione disulfide + 2 H2O. GPX5 constitute a glutathionine peroxidase-like protective system against peroxide damage in sperm membrane lipids.
References :
Vilagran I, Yeste M, Sancho S, Castillo J, Oliva R, Bonet S. Comparative analysis of boar seminal plasma proteome from different freezability ejaculates and identification of Fibronectin 1 as sperm freezability marker. Andrology. 3(2):345-56. 2015. Vilagran I, Castillo-Martín M, Prieto-Martínez N, Bonet S, Yeste M. Triosephosphate isomerase (TPI) and epididymal secretory glutathione peroxidase (GPX5) are markers for boar sperm quality. Animal reproduction science. 165:22-30. 2016.
Related websites: https://www.medchemexpress.com/antibodies.html
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