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Name :
GREM2 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
GREM2 Rabbit Polyclonal antibody. Positive IHC detected in human kidney tissue, human ovary tissue.

Tested applications :

Species reactivity :
Human, Mouse; other species not tested.

Alternative names :
CKTSF1B2 antibody; DAN domain family member 3 antibody; DAND3 antibody; GREM2 antibody; Gremlin 2 antibody; PRDC antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of GREM2 recombinant protein (Accession Number: XM_011544249). Purification method: Antigen affinity purified.

Clonality :

Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: IHC: 1:20-1:200

Background :
GREM2 represents gremlin 2, cysteine knot superfamily, homolog (Xenopus laevis)

References :
Chihara M, Nakamura T, Sakakibara N, Otsuka S, Ichii O, Kon Y. The onset of heat-induced testicular calcification in mice: involvement of the telomeric locus on chromosome 1. The American journal of pathology. 184(9):2480-92. 2014. Chihara M, Nakamura T, Otsuka-Kanazawa S, Ichii O, Elewa YH, Kon Y. Genetic factors derived from the MRL/MpJ mouse function to maintain the integrity of spermatogenesis after heat exposure. Andrology. 3(5):991-9. 2015.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
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Author: Gardos- Channel