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Name :
GRK1 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
GRK1 Rabbit Polyclonal antibody. Positive IP detected in Y79 cells. Positive WB detected in Y79 cells, mouse eye tissue. Observed molecular weight by Western-blot: 64 kDa

Tested applications :

Species reactivity :
Human, Mouse; other species not tested.

Alternative names :
GPRK1 antibody; GRK1 antibody; Rhodopsin kinase antibody; RHOK antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of GRK1 recombinant protein (Accession Number: NM_002929). Purification method: Antigen affinity purified.

Clonality :

Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:200-1:2000IP: 1:200-1:2000

Background :
GRK1(G protein-coupled receptor kinase 1) is also named as RHOK, RK, GPRK1 and belongs to the AGC Ser/Thr protein kinase family. It is involved in quenching of light-induced signal transduction in phosphoreceptor. GRK1 is a photoreceptor-specific enzyme that mediates adaptation of photoreceptors to light and protects these cells against light-induced injury.

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
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Author: Gardos- Channel