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Name :
GRK2 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
GRK2 Rabbit Polyclonal antibody. Positive IP detected in HL-60 cells. Positive WB detected in Jurkat cells, HL-60 cells. Positive FC detected in HeLa cells. Positive IHC detected in human lymphoma tissue. Observed molecular weight by Western-blot: 80 kDa

Tested applications :

Species reactivity :
Human; other species not tested.

Alternative names :
ADRBK1 antibody; BARK antibody; BARK1 antibody; Beta ARK 1 antibody; BETA ARK1 antibody; FLJ16718 antibody; GRK2 antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of GRK2 recombinant protein (Accession Number: NM_001619). Purification method: Antigen affinity purified.

Clonality :

Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:500-1:5000IP: 1:500-1:5000IHC: 1:20-1:200

Background :
ADRBK1 represents adrenergic, beta, receptor kinase 1

References :
Zhang C, Chen X, Li Y. si-RNA-Mediated Silencing of ADRBK1 Gene Attenuates Breast Cancer Cell Proliferation. Cancer biotherapy & radiopharmaceuticals. 29(8):303-9. 2014. Yang F, Yu X, Liu C. Phospho-selective mechanisms of arrestin conformations and functions revealed by unnatural amino acid incorporation and (19)F-NMR. Nature communications. 6:8202. 2015.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
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Author: Gardos- Channel