Name :
Anti-Bax Rabbit antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
Bax Rabbit polyclonal antibody
Tested applications :
WB, IHC-P, IP, FC
Species reactivity :
Human, Mouse, Rat, Hamster
Alternative names :
Immunogen :
Isotype :
Rabbit IgG
Preparation :
Antigen: A synthesized peptide derived from human Bax
Clonality :
Polyclonal
Formulation :
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage instructions :
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Applications :
WB: 1/1000-1/2000IHC: 1/50-1/200IP: 1/50FC: 1/50
Background :
Swiss-Prot Acc.Q07812.Bax is a key component for cellular induced apoptosis through mitochondrial stress. Upon apoptotic stimulation, Bax forms oligomers and translocates from the cytosol to the mitochondrial membrane. Through interactions with pore proteins on the mitochondrial membrane, Bax increases the membrane’s permeability, which leads to the release of cytochrome c from mitochondria, activation of caspase-9 and initiation of the caspase activation pathway for apoptosis.
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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