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Name :
GSDMD antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
GSDMD Rabbit Polyclonal antibody. Positive IF detected in HeLa cells. Positive IHC detected in human skin tissue. Positive WB detected in Jurkat cells. Observed molecular weight by Western-blot: 50-53 kDa

Tested applications :

Species reactivity :
Human; other species not tested.

Alternative names :
DF5L antibody; DFNA5L antibody; FKSG10 antibody; FLJ12150 antibody; gasdermin D antibody; GSDMD antibody; GSDMDC1 antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of GSDMD recombinant protein (Accession Number: NM_024736). Purification method: Antigen affinity purified.

Clonality :

Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:200-1:1000IHC: 1:20-1:200IF: 1:10-1:100

Background :
GSDMD represents gasdermin D

References :
He WT, Wan H, Hu L. Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion. Cell research. 25(12):1285-98. 2015.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
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Author: Gardos- Channel