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Name :
GSTM5 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
GSTM5 Rabbit Polyclonal antibody. Positive WB detected in mouse testis tissue, HeLa cells, mouse skeletal muscle tissue, rat skeletal muscle tissue. Positive IP detected in mouse skeletal muscle tissue. Positive IF detected in HepG2 cells. Positive IHC detected in human heart tissue. Observed molecular weight by Western-blot: 26kd

Tested applications :

Species reactivity :
Human,Mouse,Rat; other species not tested.

Alternative names :
glutathione S transferase mu 5 antibody; GST class mu 5 antibody; GSTM5 antibody; GSTM5 5 antibody; GTM5 antibody

Immunogen :
Human GSTM5 Recombinant protein (GST tag)

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of GSTM5 recombinant protein (Accession Number: NM_000851). Purification method: Antigen affinity purified.

Clonality :

Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:200-1:2000IP: 1:200-1:2000IHC: 1:20-1:200IF: 1:20-1:200

Background :
GSTM5 belongs to the GST superfamily that metabolizes a broad range of xenobiotics and carcinogens. GSTM5 is expressed in brain, testis, lung and a lesser extent in heart. No expression was detected in liver tissue.

References :
Ijiri TW, Vadnais ML, Huang AP. Thiol changes during epididymal maturation: a link to flagellar angulation in mouse spermatozoa? Andrology. 2(1):65-75. 2014. Nakajima T, Hata R, Kondo T, Takenaka S. Proteomic analysis of the hippocampus in naïve and ischemic-preconditioned rat. Journal of the neurological sciences. 358(1-2):158-71. 2015.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
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Author: Gardos- Channel