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Name :
GSTP1 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
GSTP1 Rabbit Polyclonal antibody. Positive FC detected in HepG2 cells. Positive IF detected in HepG2 cells. Positive IHC detected in human skin tissue, human liver tissue. Positive WB detected in Jurkat cells, COLO 320 cells, human brain tissue, K-562 cells, mouse brain tissue, PC-3 cells, rat brain tissue. Positive IP detected in mouse brain tissue. Observed molecular weight by Western-blot: 23-28kd

Tested applications :

Species reactivity :
Human,Mouse,Rat; other species not tested.

Alternative names :
DFN7 antibody; FAEES3 antibody; Glutathione S transferase P antibody; glutathione S transferase pi 1 antibody; GST class pi antibody; GST3 antibody; GSTP1 antibody; GSTP1 1 antibody

Immunogen :
Human GSTP1 Recombinant protein (GST tag)

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of GSTP1 recombinant protein (Accession Number: NM_000852). Purification method: Antigen affinity purified.

Clonality :

Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:500-1:5000IP: 1:200-1:2000IHC: 1:20-1:200IF: 1:20-1:200

Background :
GSTP1 represents glutathione S-transferase pi 1

References :
Cologna SM, Jiang XS, Backlund PS. Quantitative proteomic analysis of Niemann-Pick disease, type C1 cerebellum identifies protein biomarkers and provides pathological insight. PloS one. 7(10):e47845. 2012. Chang SH, Jung IS, Han GY, Kim NH, Kim HJ, Kim CW. Proteomic profiling of brain cortex tissues in a Tau transgenic mouse model of Alzheimer’s disease. Biochemical and biophysical research communications. 430(2):670-5. 2013. Yu H, Wark L, Ji H. Dietary wolfberry upregulates carotenoid metabolic genes and enhances mitochondrial biogenesis in the retina of db/db diabetic mice. Molecular nutrition & food research. 57(7):1158-69. 2013. Song J, Zhao M, Liu X, Zhu Y, Hu X, Chen F. Protection of cyanidin-3-glucoside against oxidative stress induced by acrylamide in human MDA-MB-231 cells. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 58:306-10. 2013. Shirai M, Arakawa S, Miida H. Thioacetamide-induced Hepatocellular Necrosis Is Attenuated in Diet-induced Obese Mice. Journal of toxicologic pathology. 26(2):175-86. 2013. Rojanathammanee L, Rakoczy S, Brown-Borg HM. Growth hormone alters the glutathione S-transferase and mitochondrial thioredoxin systems in long-living Ames dwarf mice. The journals of gerontology. Series A, Biological sciences and medical sciences. 69(10):1199-211. 2014. Rojanathammanee L, Rakoczy S, Kopchick J, Brown-Borg HM. Effects of insulin-like growth factor 1 on glutathione S-transferases and thioredoxin in growth hormone receptor knockout mice. Age (Dordrecht, Netherlands). 36(4):9687. 2014. Conklin DJ, Haberzettl P, Jagatheesan G. Glutathione S-transferase P protects against cyclophosphamide-induced cardiotoxicity in mice. Toxicology and applied pharmacology. 285(2):136-48. 2015.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
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Author: Gardos- Channel