Name :
HADH antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
HADH Rabbit Polyclonal antibody. Positive IHC detected in human kidney tissue, human hepat℃irrhosis tissue. Positive IF detected in HepG2 cells. Positive WB detected in HepG2 cells, Jurkat cells, mouse heart tissue, mouse kidney tissue, mouse liver tissue, mouse pancreas tissue, mouse skeletal muscle tissue. Positive IP detected in HepG2 cells. Observed molecular weight by Western-blot: 34 kDa
Tested applications :
ELISA, WB, IHC, IP, IF
Species reactivity :
Human,Mouse,Rat; other species not tested.
Alternative names :
HAD antibody; HADH antibody; HADH1 antibody; HADHSC antibody; HCDH antibody; HHF4 antibody; M/SCHAD antibody; SCHAD antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of HADH recombinant protein (Accession Number: NM_005327). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:500-1:5000IP: 1:200-1:2000IHC: 1:20-1:200IF: 1:20-1:200
Background :
HADH(Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial) is also named as HAD, HADHSC, SCHAD and belongs to the 3-hydroxyacyl-CoA dehydrogenase family. It catalyzes the reversible dehydrogenation of 3-hydroxyacyl-CoAs to their corresponding 3-ketoacyl-CoAs with concomitant reduction of NAD to NADH and exerts it highest activity toward 3-hydroxydecanoyl-CoA. . Human HADH encodes a deduced 314-amino acid protein composed of a 12-residue mitochondrial import signal peptide and a 302-residue mature HADH protein with a calculated molecular mass of 34.3 kD.
References :
Martin J, Maurhofer O, Bellance N. Disruption of the histidine triad nucleotide-binding hint2 gene in mice affects glycemic control and mitochondrial function. Hepatology (Baltimore, Md.). 57(5):2037-48. 2013.
Related websites: https://www.medchemexpress.com/antibodies.html
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