Name :
HLA-DMA antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
HLA-DMA Rabbit Polyclonal antibody. Positive WB detected in Jurkat cells. Observed molecular weight by Western-blot: 55-60kd
Tested applications :
ELISA, WB
Species reactivity :
human, mouse, rat; other species not tested.
Alternative names :
HLADM antibody; HLA DMA antibody; DMA antibody; DAMC 226H3.5 001 antibody; DASS 67H14.8 001 antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of HLA-DMA recombinant protein (Accession Number: NM_006120). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:500-1:5000
Background :
HLA-DMA and -DMB form a functional heterodimer that is critical in the pathway of class II antigen presentation. HLA-DM plays a critical role in catalyzing the release of Class II HLA-associated invariant chain-derived peptides (CLIP) from newly synthesized class II HLA molecules and freeing the peptide binding site for acquisition of antigenic peptides. This antibody recognize the 33kd HLA-DMA and the 50-60kd dimer in Western blotting.
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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