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Name :
HLA-DRB1 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
HLA-DRB1 Rabbit Polyclonal antibody. Positive WB detected in human spleen tissue, A375 cells, Raji cells. Positive IP detected in Raji cells. Observed molecular weight by Western-blot: 27-30 kDa

Tested applications :

Species reactivity :
Human; other species not tested.

Alternative names :
DR4 antibody; DRB1 antibody; DW2.2/DR2.2 antibody; FLJ75017 antibody; FLJ76359 antibody; HLA DR1B antibody; HLA DRB antibody; HLA DRB1 antibody; HLA DRB1* antibody; HLA DRB2 antibody; HLA-DRB1 antibody; MHC class II antigen DRB1*15 antibody; SS1 antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of HLA-DRB1 recombinant protein (Accession Number: XM_047444769). Purification method: Antigen affinity purified.

Clonality :

Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:500-1:5000IP: 1:200-1:2000

Background :
HLA-DRB1 represents major histocompatibility complex, class II, DR beta 1

References :
Semini G, Hildmann A, Klein A. Inositol-C2-PAF down-regulates components of the antigen presentation machinery in a 2D-model of epidermal inflammation. Biochemical pharmacology. 87(3):477-88. 2014.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
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Author: Gardos- Channel