Name :
HLTF Polyclonal Antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
Polyclonal antibody to HLTF
Tested applications :
WB
Species reactivity :
Human
Alternative names :
HLTF antibody; HIP116 antibody; HIP116A antibody; HLTF1 antibody; RNF80 antibody; SMARCA3 antibody; SNF2L3 antibody; ZBU1 antibody; helicase-like transcription factor antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 726-1009 of human HLTF (NP_620636.1).
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage instructions :
Store at -20℃. Avoid freeze / thaw cycles.
Applications :
WB 1:500 – 1:2000
Background :
Has both helicase and E3 ubiquitin ligase activities. Possesses intrinsic ATP-dependent nucleosome-remodeling activity; This activity may be required for transcriptional activation or repression of specific target promoters (By similarity). These may include the SERPINE1 and HIV-1 promoters and the SV40 enhancer, to which this protein can bind directly. Plays a role in error-free postreplication repair (PRR) of damaged DNA and maintains genomic stability through acting as a ubiquitin ligase for ‘Lys-63’-linked polyubiquitination of chromatin-bound PCNA.
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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