Name :
HMOX2 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
HMOX2 Rabbit Polyclonal antibody. Positive IP detected in Raji cells. Positive WB detected in HepG2 cells, K-562 cells, mouse spleen tissue, Raji cells. Positive IHC detected in human lymphoma tissue. Positive IF detected in Hela cells. Observed molecular weight by Western-blot: 36 kDa
Tested applications :
ELISA, IHC, IF, WB, IP
Species reactivity :
Human,Mouse,Rat; other species not tested.
Alternative names :
heme oxygenase (decycling) 2 antibody; Heme oxygenase 2 antibody; HMOX2 antibody; HO 2 antibody; HO2 antibody
Immunogen :
Human HMOX2 Recombinant protein (His tag)
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of HMOX2 recombinant protein (Accession Number: XM_017023196). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:200-1:2000IP: 1:200-1:2000IHC: 1:20-1:200IF: 1:20-1:200
Background :
Heme oxygenase is the rate-limiting enzyme in the heme degradative pathway. There are 2 isozymic forms of heme oxygenase, an inducible heme oxygenase-1 (HMOX1) and a constitutive heme oxygenase-2 (HMOX2). Down-regulation of HMOX2 is associated with the increased expression of HMOX1 in human cell lines. HMOX2 is also named as HO-2 and could be implicated in the production of carbon monoxide in brain where it could act as a neurotransmitter.
References :
Magierowska K, Magierowski M, Hubalewska-Mazgaj M. Carbon Monoxide (CO) Released from Tricarbonyldichlororuthenium (II) Dimer (CORM-2) in Gastroprotection against Experimental Ethanol-Induced Gastric Damage. PloS one. 10(10):e0140493. 2015. Guo D, Liang S, Wang S. Role of epithelial Na+ channels in endothelial function. Journal of cell science. 129(2):290-7. 2016.
Related websites: https://www.medchemexpress.com/antibodies.html
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