Name :
HNMT antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
HNMT Rabbit Polyclonal antibody. Positive WB detected in human liver tissue, mouse liver tissue. Positive IF detected in MCF-7 cells. Positive IHC detected in human lymphoma tissue. Observed molecular weight by Western-blot: 33 kDa
Tested applications :
ELISA, WB, IHC, IF
Species reactivity :
Human, Mouse, Rat; other species not tested.
Alternative names :
histamine N methyltransferase antibody; HMT antibody; HNMT antibody; HNMT S1 antibody; HNMT S2 antibody
Immunogen :
Human HNMT Recombinant protein (His tag)
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of HNMT recombinant protein (Accession Number: NM_006895). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:500-1:5000IHC: 1:20-1:200IF: 1:10-1:100
Background :
HNMT, a histamine-metabolizing enzyme, inactivates histamine by N-methylation. It plays an important role in degrading histamine and in regulating the airway response to histamine. HNMT in human astrocytes play a role in the regulation of extraneuronal histamine concentration and the activities of histaminergic neurons.
References :
Yoshikawa T, Naganuma F, Iida T. Molecular mechanism of histamine clearance by primary human astrocytes. Glia. 61(6):905-16. 2013.
Related websites: https://www.medchemexpress.com/antibodies.html
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