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Name :
HNRNPU antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
HNRNPU Rabbit Polyclonal antibody. Positive IF detected in HeLa cells. Positive IP detected in HeLa cells. Positive WB detected in Jurkat cells, HEK-293 cells, HeLa cells, K-562 cells, mouse lung tissue. Observed molecular weight by Western-blot: 120 kDa

Tested applications :

Species reactivity :
Human,Mouse,Rat; other species not tested.

Alternative names :
hnRNP U antibody; HNRNPU antibody; HNRPU antibody; p120 antibody; pp120 antibody; SAF A antibody; SAFA antibody; Scaffold attachment factor A antibody; U21.1 antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of HNRNPU recombinant protein (Accession Number: XM_017001117). Purification method: Antigen affinity purified.

Clonality :

Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:1000-1:10000IP: 1:200-1:2000IF: 1:20-1:200

Background :
HNRNPU represents heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)

References :
Suzuki H, Shibagaki Y, Hattori S, Matsuoka M. Nuclear TDP-43 causes neuronal toxicity by escaping from the inhibitory regulation by hnRNPs. Human molecular genetics. 24(6):1513-27. 2015.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
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Author: Gardos- Channel