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Name :
HOXA1 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
HOXA1 Rabbit Polyclonal antibody. Positive WB detected in Transfected HEK-293 cells.

Tested applications :

Species reactivity :
Human,Mouse,Rat; other species not tested.

Alternative names :
BSAS antibody; homeobox A1 antibody; Homeobox protein Hox 1F antibody; Homeobox protein Hox A1 antibody; HOX1 antibody; HOX1F antibody; HOXA1 antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of HOXA1 recombinant protein (Accession Number: NM_005522). Purification method: Antigen affinity purified.

Clonality :

Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:200-1:2000

Background :
HOXA, a member of HOX family, encoded by HOX genes, is a transcriptional factors that plays important role in organogenesis during development via the regualtion of proliferation, differentiation, survival, migration and invasion.HOXA1 influences numerous cellular processes including proliferation, apoptosis, and the epithelial–mesenchymal transition (EMT), and HOXA1 overexpression is sufficient for malignant transformation of nontumorigenic epithelial cells.

References :
Zha TZ, Hu BS, Yu HF, Tan YF, Zhang Y, Zhang K. Overexpression of HOXA1 correlates with poor prognosis in patients with hepatocellular carcinoma. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. 33(6):2125-34. 2012.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
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Author: Gardos- Channel