Name :
Anti-BGN antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
Rabbit Polyclonal to Human BGN
Tested applications :
IHC-P
Species reactivity :
Human Biglycan
Alternative names :
Biglycan antibody; BGN antibody; DSPG1 antibody; PG-S1 antibody; PGI antibody; SLRR1A antibody; biglycan proteoglycan antibody; bone/cartilage proteoglycan I antibody; dermatan sulphate proteoglycan I antibody; small antibody; Biglycan antibody; Bgn antibody; RP23-95K12.7 antibody; BG antibody; DSPG1 antibody; PG-S1 antibody; PGI antibody; SLRR1A antibody; bone/cartilage proteoglycan I antibody; PGI antibody; DSPG1 antibody; PG-S1 antibody; SLRR1A antibody; BG antibody; PGI antibody; DSPG1 antibody; PG-S1 antibody; SLRR1A antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
Produced in rabbits immunized with a synthetic peptide corresponding to the C-terminus of the Human Biglycan, and purified by antigen affinity chromatography.
Clonality :
Polyclonal
Formulation :
0.2 μm filtered solution in PBS
Storage instructions :
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Applications :
IHC-P: 0.1-2 μg/mL
Background :
Biglycan, also known as PG-S1 and BGN, is a a small leucine-rich repeat proteoglycan (SLRP). It can be detected in a variety of extracellular matrix tissues, including bone, cartilage and tendon. Biglycan consists of a protein core containing leucine-rich repeat regions and two glycosaminoglycan (GAG) chains consisting of either chondroitin sulfate (CS) or dermatan sulfate (DS). Non-glycanated forms of biglycan (no GAG chains) increase with age in human articular cartilage. Biglycan interacts with collagen, both via the core protein and GAG chains. Biglycan plays a role in the mineralisation of bone. Biglycan core protein binds to the growth factors BMP-4 and influences its bioactivity.
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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