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Name :
HPRT1 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
HPRT1 Rabbit Polyclonal antibody. Positive IF detected in Hela cells. Positive IHC detected in human brain tissue, human pancreas tissue. Positive FC detected in HeLa cells. Positive WB detected in HepG2 cells, A549 cells, HeLa cells, Jurkat cells, MCF7 cells, mouse liver tissue, NIH/3T3 cells, rat brain tissue, Y79 cells. Positive IP detected in mouse liver tissue. Observed molecular weight by Western-blot: 24-28 kDa

Tested applications :

Species reactivity :
Human,Mouse,Rat; other species not tested.

Alternative names :
HGPRT antibody; HGPRTase antibody; HPRT antibody; HPRT1 antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of HPRT1 recombinant protein (Accession Number: NM_000194). Purification method: Antigen affinity purified.

Clonality :

Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:1000-1:10000IP: 1:500-1:5000IHC: 1:20-1:200IF: 1:10-1:100

Background :
HPRT1 represents hypoxanthine phosphoribosyltransferase 1

References :
Owens GC, Huynh MN, Chang JW. Differential expression of interferon-γ and chemokine genes distinguishes Rasmussen encephalitis from cortical dysplasia and provides evidence for an early Th1 immune response. Journal of neuroinflammation. 10:56. 2013.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
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Author: Gardos- Channel