Name :
HPS1 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
HPS1 Rabbit Polyclonal antibody. Positive WB detected in L02 cells, HEK-293 cells, K-562 cells, Raji cells, Transfected HEK-293 cells, Y79 cells. Observed molecular weight by Western-blot: 70-79 kDa
Tested applications :
ELISA, WB
Species reactivity :
Human; other species not tested.
Alternative names :
Hermansky Pudlak syndrome 1 antibody; HPS antibody; HPS1 antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of HPS1 recombinant protein (Accession Number: NM_182639). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:200-1:2000
Background :
HPS1, also named as Hermansky-Pudlak syndrome 1 protein, is a 700 amino acid protein, which is a component of multiple cytoplasmic organelles. HPS1 is Apparently crucial for their normal development and function and involved in intracellular protein sorting.HPS1 is involved in the biogenesis of early melanosomes.
References :
Cullinane AR, Yeager C, Dorward H. Dysregulation of galectin-3. Implications for Hermansky-Pudlak syndrome pulmonary fibrosis. American journal of respiratory cell and molecular biology. 50(3):605-13. 2014. Ikawa Y, Hess R, Dorward H. In vitro functional correction of Hermansky-Pudlak Syndrome type-1 by lentiviral-mediated gene transfer. Molecular genetics and metabolism. 114(1):62-5. 2015.
Related websites: https://www.medchemexpress.com/antibodies.html
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