Name :
ACD Polyclonal Antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
Polyclonal antibody to ACD
Tested applications :
WB
Species reactivity :
Human, Mouse, Rat
Alternative names :
ACD antibody; PIP1 antibody; PTOP antibody; TINT1 antibody; TPP1 antibody; adrenocortical dysplasia protein homolog antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human ACD (NP_001075955.1).
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage instructions :
Store at -20℃. Avoid freeze / thaw cycles.
Applications :
WB 1:500 – 1:2000
Background :
Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends. Without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Promotes binding of POT1 to single-stranded telomeric DNA. Modulates the inhibitory effects of POT1 on telomere elongation. The ACD-POT1 heterodimer enhances telomere elongation by recruiting telomerase to telomeres and increasing its processivity. May play a role in organogenesis.
References :
Related websites: https://www.medchemexpress.com/antibodies.html
Popular product recommendations:
Bimagrumab
Galiximab
TRITC-conjugated AffiniPure Goat Anti-Mouse IgG H&L: TRITC-conjugated AffiniPure Goat Anti-Mouse IgG H&Lis an -conjugated, goat-derived anti-mouse IgG antibody. TRITC-conjugated AffiniPure Goat Anti-Mouse IgG H&L conjugates the light and heavy chains of mouse IgG antibodies for use in ICC/IF, FC experiments in the mouse context.
