Name :
IRF7 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
IRF7 Rabbit Polyclonal antibody. Positive IP detected in HEK-293 cells. Positive WB detected in HEK-293 cells. Positive IHC detected in human tonsillitis tissue. Observed molecular weight by Western-blot: 80 kDa
Tested applications :
ELISA, WB, IHC, IP
Species reactivity :
Human; other species not tested.
Alternative names :
interferon regulatory factor 7 antibody; IRF 7 antibody; IRF 7H antibody; IRF7 antibody; IRF7A antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of IRF7 recombinant protein (Accession Number: XM_005252906). Purification method: Antigen Affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:200-1:2000IP: 1:200-1:2000IHC: 1:20-1:200
Background :
IRF-7 (interferon regulatory factor 7) is a member of the interferon regulatory transcription factor (IRF) family. IRF-7 has been shown to play a role in the transcriptional activation of virus-inducible cellular proteins, including interferon beta chain proteins. Inducible expression of IRF-7 is largely restricted to lymphoid tissue. Four transcript variants encoding distinct isoforms (A,B,C and D) have been identified for this (PMID:9786932).The active IRF7A exists as a dimer form ~80 kDa(PMID:11073981). The MW 67-70 kDa has been reported in some papers (PMID:9786932; 22951831).Various posttranslational modifications of IRF7 including phosphorylation, ubiquitination, sumoylation and acetylation are identified (PMID:22951831).This antibody is a rabbit polyclonal antibody raised against the C-terminal 349 amino acid residues of human IRF7 D.
References :
Weng XG, Song QJ, Wu Q, Liu MC, Wang ML, Wang JF. Genetic characterization of bovine viral diarrhea virus strains in Beijing, China and innate immune responses of peripheral blood mononuclear cells in persistently infected dairy cattle. Journal of veterinary science. 16(4):491-500. 2015.
Related websites: https://www.medchemexpress.com/antibodies.html
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