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Name :
ITLN1 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
ITLN1 Rabbit Polyclonal antibody. Positive IP detected in mouse appendix tissue. Positive WB detected in mouse colon tissue, human heart tissue, human ileum tissue, mouse thymus tissue. Positive IHC detected in human small intestine tissue, human heart tissue. Observed molecular weight by Western-blot: 35-40kd

Tested applications :
ELISA, WB, IHC, IP

Species reactivity :
Human,Mouse,Rat; other species not tested.

Alternative names :
Endothelial lectin HL 1 antibody; FLJ20022 antibody; Galactofuranose binding lectin antibody; hIntL antibody; HL 1 antibody; HL1 antibody; Intelectin 1 antibody; INTL antibody; ITLN antibody; ITLN 1 antibody; ITLN1 antibody; LFR antibody; omentin antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of ITLN1 recombinant protein (Accession Number: NM_017625). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:500-1:5000IP: 1:200-1:2000IHC: 1:20-1:200

Background :
ITLN1, also named as INTL, ITLN and LFR, has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. It may play a role in the defense system against microorganisms. ITLN1 may be involved in iron metabolism. The expression levels of ITLN1 is significantly different between the GPG and PPG (p<0.05).

References :
Kim HJ, Kang UB, Lee H. Profiling of differentially expressed proteins in stage IV colorectal cancers with good and poor outcomes. Journal of proteomics. 75(10):2983-97. 2012. Wangkanont K, Wesener DA, Vidani JA, Kiessling LL, Forest KT. Structures of Xenopus embryonic epidermal lectin reveal a conserved mechanism of microbial glycan recognition. The Journal of biological chemistry. 2016.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel