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Name :
KCNN4 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
KCNN4 Mouse Monoclonal antibody. Positive WB detected in human blood tissue. Observed molecular weight by Western-blot: 48 kDa

Tested applications :
ELISA, WB

Species reactivity :
Human, Mouse, Rat; other species not tested.

Alternative names :
hIKCa1 antibody; hKCa4 antibody; hSK4 antibody; IK1 antibody; IKCA1 antibody; KCa3.1 antibody; KCA4 antibody; KCNN4 antibody; Putative Gardos channel antibody; SK4 antibody; SKCa 4 antibody; SKCa4 antibody

Immunogen :

Isotype :
Mouse IgG2a

Preparation :
This antibody was obtained by immunization of KCNN4 recombinant protein (Accession Number: NM_002250). Purification method: Protein A purified.

Clonality :
Monoclonal

Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:500-1:5000

Background :
The intermediate conductance calcium-activated potassium channel KCNN4, also known as KCa3.1, IK1, or SK4, is a member of the potassium channel KCNN family. KCNN4 is expressed in T cells, mast cells, macrophages, erythrocytes, vascular smooth muscle cells, airway smooth muscle cells, intestinal and airway epithelial cells (PMID: 19681865; 21493782). Functionally, KCNN4 plays a key role in calcium-dependent cell functions, such as proliferation, activation, and migration, in a broad range of cell types (PMID: 21493782).

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel