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Name :
KRT2 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
KRT2 Rabbit Polyclonal antibody. Positive WB detected in A431 cells. Observed molecular weight by Western-blot: 65 kDa

Tested applications :
ELISA, WB

Species reactivity :
Human; other species not tested.

Alternative names :
CK 2e antibody; Cytokeratin 2e antibody; Epithelial keratin 2e antibody; K2e antibody; keratin 2 antibody; Keratin 2 epidermis antibody; Keratin 2e antibody; KRT2 antibody; KRT2A antibody; KRT2E antibody; KRTE antibody; Type II keratin Kb2 antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of KRT2 recombinant protein (Accession Number: NM_000423). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:500-1:5000

Background :
Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells. Keratin expression is highly regulated, tissue specific, and varies according to cell-state. Type I keratins consist of acidic, low molecular weight proteins with MW ranging from 40 kDa (KRT19) to 64 kDa (KRT9). Type 2 keratins consist of basic or neutral, high molecular weight proteins with MW from 52 kDa (KRT8) to 67 kDa (KRT18).Keratin 2 is a type II cytokeratin. It is found largely in the upper spinous layer of epidermal keratinocytes, and also in other regions, notably the epidermis covering the knee, thigh, and groin.

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel