Name :
GNE antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
GNE Rabbit Polyclonal antibody. Positive IHC detected in human kidney tissue, human placenta tissue. Positive WB detected in Jurkat cells. Observed molecular weight by Western-blot: 79 kDa
Tested applications :
ELISA, WB, IHC
Species reactivity :
Human; other species not tested.
Alternative names :
DMRV antibody; GLCNE antibody; GNE antibody; IBM2 antibody; ManAc kinase antibody; Uae1 antibody; UDP GlcNAc 2 epimerase antibody
Immunogen :
Human GNE Recombinant protein (GST tag)
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of GNE recombinant protein (Accession Number: NM_005476). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:500-1:5000IHC: 1:20-1:200
Background :
The bifunctional enzyme UDP-N-acetylglucosamine-2-epimerase/N-acetylmannosamine kinase (GNE) is essential for early embryonic development and catalyzes the rate limiting step in sialic acid biosynthesis. It plays an important role in neuronal cell and brain development, and is strongly involved in cardiac tissue and skeletal muscle early survival and organization.. This protein has 5 isoforms produced by alternative splicing.
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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