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Name :
GOT2 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
GOT2 Rabbit Polyclonal antibody. Positive FC detected in HEK-293 cells. Positive IF detected in MCF-7 cells. Positive IHC detected in human skin cancer tissue, human kidney tissue, human liver tissue, human skin tissue. Positive WB detected in mouse brain tissue, A431 cells, HepG2 cells, mouse heart tissue, mouse spleen tissue, rat brain tissue. Observed molecular weight by Western-blot: 43-45 kDa

Tested applications :

Species reactivity :
Human,Mouse,Rat; other species not tested.

Alternative names :
FABP 1 antibody; FABPpm antibody; Fatty acid binding protein antibody; FLJ40994 antibody; GOT2 antibody; KAT4 antibody; KATIV antibody; mAspAT antibody; mitAAT antibody; Transaminase A antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of GOT2 recombinant protein (Accession Number: NM_002080). Purification method: Antigen affinity purified.

Clonality :

Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:500-1:5000IHC: 1:20-1:200IF: 1:20-1:200

Background :
GOT2 represents glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2)

References :
Sun L, Song L, Wan Q. cMyc-mediated activation of serine biosynthesis pathway is critical for cancer progression under nutrient deprivation conditions. Cell research. 25(4):429-44. 2015.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
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Author: Gardos- Channel