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Name :
GRB7 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
GRB7 Rabbit Polyclonal antibody. Positive IP detected in A431 cells. Positive WB detected in A431 cells, HEK-293 cells, mouse brain tissue. Positive IF detected in A431 cells. Observed molecular weight by Western-blot: 60-70 kDa

Tested applications :

Species reactivity :
Human, Mouse; other species not tested.

Alternative names :
B47 antibody; GRB7 antibody; GRB7 adapter protein antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of GRB7 recombinant protein (Accession Number: NM_001030002). Purification method: Protein A purified.

Clonality :

Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:500-1:5000IP: 1:200-1:2000IF: 1:10-1:100

Background :
Grb7 belongs to a family of adapter proteins. This family, including Grb10, Grb7 and Grb 14, contains a praline-rich, a RA, a PH, a BPS and SH2 domain. Grb7 associate with a number of receptors including EGFR and FAK. Functions of Grb7 include mobility because it associates receptors such FAK, and direct evidence from overexpression of this proteins.This antibody recognize the N-terminal of GRB7.

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
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Author: Gardos- Channel