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Name :
GSNOR,ADH5 antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
GSNOR,ADH5 Mouse Monoclonal antibody. Positive IHC detected in human pancreas cancer tissue, human testis tissue. Positive IF detected in HepG2 cells. Positive WB detected in fetal human brain tissue, human testis tissue. Observed molecular weight by Western-blot: 40 kDa

Tested applications :

Species reactivity :
Human; other species not tested.

Alternative names :
ADH 3 antibody; ADH5 antibody; ADHX antibody; Alcohol dehydrogenase 5 antibody; Alcohol dehydrogenase class 3 antibody; FALDH antibody; FDH antibody; GSH FDH antibody; GSNOR antibody; GSNOR antibody; ADH5 antibody

Immunogen :
Human GSNOR,ADH5 Recombinant protein (His tag)

Isotype :
Mouse IgG1

Preparation :
This antibody was obtained by immunization of GSNOR,ADH5 recombinant protein (Accession Number: NM_000671). Purification method: Protein G purified.

Clonality :

Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:1000-1:10000IHC: 1:20-1:200IF: 1:20-1:200

Background :
ADH5, also named as ADHX, FDH FALDH GSH-FDH ADH3 and GSNOR, belongs to the zinc-containing alcohol dehydrogenase family and Class-III subfamily. It is remarkably ineffective in oxidizing ethanol, but it readily catalyzes the oxidation of long-chain primary alcohols and the oxidation of S-(hydroxymethyl) glutathione. ADH5 mediates multiple cardiovascular functions. It plays in regulating heterocellular communication in the artery wall. (PMID:21071693). ADH5 immunostaining is distributed in both the nucleus and cytoplasm of the retinal ganglion cells(PMID:22117533).

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
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Author: Gardos- Channel