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Name :
GSPT2 Polyclonal Antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
Polyclonal antibody to GSPT2

Tested applications :
WB

Species reactivity :
Human, Mouse

Alternative names :
GSPT2 antibody; ERF3B antibody; GST2 antibody; G1 to S phase transition 2 antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
Antigen: A synthetic Peptide of human GSPT2

Clonality :
Polyclonal

Formulation :
PBS with 0.02% sodium azide, pH7.3.

Storage instructions :
Store at 4℃. Avoid freeze / thaw cycles.

Applications :
WB 1:500 – 1:1000

Background :
Involved in translation termination in response to the termination codons UAA, UAG and UGA. May play a role as a potent stimulator of the release factor activity of ETF1. Exhibits GTPase activity, which is ribosome- and ETF1-dependent. May play a role in cell cycle progression. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel