Name :
GSR antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
GSR Rabbit Polyclonal antibody. Positive WB detected in Jurkat cells, HeLa cells, human placenta tissue, mouse lung tissue. Positive IP detected in HeLa cells. Positive IF detected in MCF-7 cells. Observed molecular weight by Western-blot: 52-55 kDa
Tested applications :
ELISA, WB, IF, IP
Species reactivity :
Human,Mouse,Rat; other species not tested.
Alternative names :
GLUR antibody; glutathione reductase antibody; GRase antibody; GRD1 antibody; GSR antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of GSR recombinant protein (Accession Number: NM_000637). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:500-1:5000IP: 1:200-1:2000IF: 1:10-1:100
Background :
GSR(Glutathione reductase) is also named as GLUR, GRD1 and belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.It was first found in a black American a variant red cell GSR characterized by greater electrophoretic mobility and enzyme activity per unit of hemoglobin than the normal.This protein maintains high levels of reduced glutathione in the cytosol.It has 5 isoforms produced by alternative splicing and alternative initiation.It can also exsit as a homodimer with the molecular weight of 110KDa(PMID:8631352).This antibody is specific to GSR.
References :
Wu H, Xiao Y, Zhang S. The Ets transcription factor GABP is a component of the hippo pathway essential for growth and antioxidant defense. Cell reports. 3(5):1663-77. 2013.
Related websites: https://www.medchemexpress.com/antibodies.html
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