Name :
Anti-Bcl10 (6F7) Mouse antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
Bcl10 (6F7) Mouse monoclonal antibody
Tested applications :
WB, IHC-P, ICC/IF, FC
Species reactivity :
Human, Mouse
Alternative names :
Immunogen :
Isotype :
Mouse IgG1
Preparation :
Antigen: Purified recombinant fragment of human BCL-10 expressed in E. Coli.
Clonality :
Monoclonal
Formulation :
Ascitic fluid containing 0.03% sodium azide.
Storage instructions :
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Applications :
WB: 1/500 – 1/2000IHC: 1/200 – 1/1000ICC: 1/200 – 1/1000FC: 1/200 – 1/400ELISA: 1/10000
Background :
Swiss-Prot Acc.O95999.Bcl-10 (B-cell CLL/lymphoma 10), also known as CLAP, Me10, CIPER, c-E10, CARMEN. Entrez Protein NP_003912. It is a protein containing a caspase recruitment domain (CARD). It plays an important role in apoptosis and activating NF-kappaB. The research suggested that it interacted with other CARD domain containing proteins including CARD9, 10, 11 and 14, which were thought to function as upstream regulators in NF-kappaB signaling. Bcl-10 is found to form a complex with MALT1 which encoded by another gene known to be translocated in MALT lymphoma. MALT1 and Bcl-10 are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy.
References :
Related websites: https://www.medchemexpress.com/antibodies.html
Popular product recommendations:
FEN1 Antibody (YA765)
STAT2 Antibody (YA057)
Histone H3 (mono methyl R2)Antibody: Histone H3 (mono methyl R2)Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 15 kDa, targeting to Histone H3 (mono methyl R2). It can be used for WB,ICC/IF assays with tag free, in the background of Human, Mouse.
