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Name :
GYPC antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
GYPC Rabbit Polyclonal antibody. Positive WB detected in human blood tissue. Observed molecular weight by Western-blot: 37 kDa

Tested applications :

Species reactivity :
Human; other species not tested.

Alternative names :
CD236 antibody; CD236R antibody; GLPC antibody; GlycOConnectin antibody; Glycophorin C antibody; Glycophorin D antibody; Glycoprotein beta antibody; GPC antibody; GPD antibody; GYPC antibody; GYPD antibody; PAS 2 antibody; Sialoglycoprotein D antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of GYPC recombinant protein (Accession Number: NM_002101). Purification method: Antigen affinity purified.

Clonality :

Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:1000-1:10000

Background :
Glycophorin-C, encoded by the GYPC gene, is a minor sialoglycoprotein in human erythrocyte membranes. Glycophorin-C interacts with protein 4.1R (EPB41) and plays an important role in regulating the mechanical stability of red cells. Glycophorin C acts as the receptor for the Plasmodium falciparum erythrocyte binding ligand PfEBP-2 (baebl). Glycophorin-D, also encoded by the GYPC gene, is now known as a variant of Glycophorin-C. This antibody is raised against the full-length protein of human Glycophorin-C. The apparent molecular weight of Glycophorin-C is lager than the calculated molecular weight due to glycosylation.

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
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Author: Gardos- Channel