Name :
Hephaestin antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
Hephaestin Rabbit Polyclonal antibody. Positive IHC detected in human pancreas cancer tissue.
Tested applications :
ELISA, IHC
Species reactivity :
Human,Mouse,Rat; other species not tested.
Alternative names :
CPL antibody; HEPH antibody; Hephaestin antibody; KIAA0698 antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of Hephaestin recombinant protein (Accession Number: NM_001367233). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: IHC: 1:20-1:200
Background :
Hephaestin, also named as KIAA0698, belongs to the multicopper oxidase family. It is provied as ferroxidase of cellular iron export. HEPH is implicated in iron homeostasis and may mediate iron efflux associated to ferroportin 1. HEPE is active in placenta but may not play a key role in placental iron transport.
References :
Li YQ, Bai B, Cao XX, Yan H, Zhuang GH. Ferroportin 1 and hephaestin expression in BeWo cell line with different iron treatment. Cell biochemistry and function. 30(3):249-55. 2012.
Related websites: https://www.medchemexpress.com/antibodies.html
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