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Name :
Anti-beta 2 Microglobulin (5G12) Mouse antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
beta 2 Microglobulin (5G12) Mouse monoclonal antibody

Tested applications :

Species reactivity :

Alternative names :

Immunogen :

Isotype :

Preparation :
Antigen: Purified recombinant fragment of human B2M (AA: 21-100) expressed in E. Coli.

Clonality :

Formulation :
Purified antibody in PBS with 0.05% sodium azide.

Storage instructions :
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

Applications :
WB: 1/500 – 1/2000IHC: 1/200 – 1/1000FC: 1/200 – 1/400ELISA: 1/10000

Background :
Swiss-Prot Acc.P61769.This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
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Author: Gardos- Channel