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Name :
HINFP antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
HINFP Rabbit Polyclonal antibody. Positive IF detected in Hela cells, L02 cells. Positive WB detected in human liver tissue, L02 cells. Observed molecular weight by Western-blot: 60 kDa

Tested applications :
ELISA, WB, IF

Species reactivity :
Human,Mouse,Rat; other species not tested.

Alternative names :
DKFZp434F162 antibody; HiNF P antibody; HINFP antibody; Histone nuclear factor P antibody; MIZF antibody; ZNF743 antibody

Immunogen :

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of HINFP recombinant protein (Accession Number: NM_015517). Purification method: Antigen affinity purified.

Clonality :
Polyclonal

Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:200-1:1000IF: 1:10-1:100

Background :
Methylation of CpG dinucleotides is the major epigenetic modification in higher eukaryotic genomes. MIZF interacts with MBD2, a methyl-CpG-binding protein playing a critical role in DNA methylation-mediated transcriptional repression. MIZF functions as a negative regulator of transcription by binding to MBD2 and recruiting histone deacetylase (HDAC)-containing complexes. MIZF mRNA is present in various human tissues and cell lines and expressed as a 60kd protein.

References :

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: Gardos- Channel