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Name :
Histone H2B antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
Histone H2B Rabbit Polyclonal antibody. Positive WB detected in Transfected HEK-293 cells. Positive IP detected in HEK-293 cells. Positive IHC detected in human pancreas tissue, human breast cancer tissue.

Tested applications :

Species reactivity :
Human; other species not tested.

Alternative names :
GL105 antibody; H2B antibody; H2B.1 antibody; H2B/q antibody; H2BFQ antibody; HIST2H2BE antibody; histone cluster 2 antibody; H2be antibody; Histone H2B antibody; Histone H2B GL105 antibody; Histone H2B type 2 E antibody; Histone H2B.q antibody

Immunogen :
Human Histone H2B Recombinant protein (His tag)

Isotype :
Rabbit IgG

Preparation :
This antibody was obtained by immunization of Histone H2B recombinant protein (Accession Number: NM_003528). Purification method: Antigen affinity purified.

Clonality :

Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions :
Store at -20℃. DO NOT ALIQUOT

Applications :
Recommended Dilution: WB: 1:500-1:5000IP: 1:200-1:2000IHC: 1:20-1:200

Background :
HIST2H2BE represents histone cluster 2, H2be

References :
Whitcomb SJ, Fierz B, McGinty RK. Histone monoubiquitylation position determines specificity and direction of enzymatic cross-talk with histone methyltransferases Dot1L and PRC2. The Journal of biological chemistry. 287(28):23718-25. 2012.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
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Author: Gardos- Channel